Anavar and testosterone levels

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The oral bioavailability of oxandrolone is 97%. [2] Its plasma protein binding is 94 to 97%. [2] The drug is metabolized primarily by the kidneys and to a lesser extent by the liver . [1] [2] Oxandrolone is the only AAS that is not primarily or extensively metabolized by the liver, and this is thought to be related to its diminished hepatotoxicity relative to other AAS. [1] [3] Its elimination half-life is reported as to  hours but is extended to  hours in the elderly. [2] [3] Approximately 28% of an oral dose of oxandrolone is eliminated unchanged in the urine and 3% is excreted in the feces . [3]

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References
1. Rudman D, Feller AG, Nagraj HS, et al. Effects of human growth hormone in men over 60 years old. N Engl J Med 1990;323:1-6
2. Blackman, MR, et al. Effects of growth hormone and/or sex steroid administration on body composition in healthy elderly women and men; 1999 Endrocrine Society conference, San Diego, California
3. N Engl J Med 1990; 323:1-6July 5, 1990
4. J Clin Invest. 1993 Feb;91(2):391-6.
5. 5. Horm Res. 2002;58 Suppl [3:43] -8.
6. Am J Sports Med. 1984 Jan-Feb;12(1):31-8.
7. Biochim Biophys Acta. 1995 May 11;1244(1):117-20 .
8. Sports Med. 2004;34(8):513-54.
9. Enzyme induction by oral testosterone. Johnsen SG, Kampmann JP, Bennet EP, Jorgensen F. 1976 Clin Pharmacol Ther [20:23] 3-237.
10. Expert Opin Drug Saf . 2012 Sep;11(5):779-95. doi: /. Epub 2012 Aug 6.
11. Addiction. 2015 May;110(5):823-31. doi: /. Epub 2015 Feb 25

In either case, both men and women, Anavar can be used for far longer than most oral anabolic steroids due to its low liver toxicity rating and further as it does not appear to taper off in benefit as fast as many other oral anabolic steroids. The majority of Anavar users will supplement for 6-8 weeks but longer durations of 12 weeks are not uncommon, especially during female contest preparation time. Keep in mind, the leaner you are the greater the results will be, meaning, they will be far more pronounced; for this reason most women will choose Anavar during the latter half of their diet to reap the greatest reward.

Anavar and testosterone levels

anavar and testosterone levels

References
1. Rudman D, Feller AG, Nagraj HS, et al. Effects of human growth hormone in men over 60 years old. N Engl J Med 1990;323:1-6
2. Blackman, MR, et al. Effects of growth hormone and/or sex steroid administration on body composition in healthy elderly women and men; 1999 Endrocrine Society conference, San Diego, California
3. N Engl J Med 1990; 323:1-6July 5, 1990
4. J Clin Invest. 1993 Feb;91(2):391-6.
5. 5. Horm Res. 2002;58 Suppl [3:43] -8.
6. Am J Sports Med. 1984 Jan-Feb;12(1):31-8.
7. Biochim Biophys Acta. 1995 May 11;1244(1):117-20 .
8. Sports Med. 2004;34(8):513-54.
9. Enzyme induction by oral testosterone. Johnsen SG, Kampmann JP, Bennet EP, Jorgensen F. 1976 Clin Pharmacol Ther [20:23] 3-237.
10. Expert Opin Drug Saf . 2012 Sep;11(5):779-95. doi: /. Epub 2012 Aug 6.
11. Addiction. 2015 May;110(5):823-31. doi: /. Epub 2015 Feb 25

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