Anticoagulants: Patients on anticoagulants such as warfarin should be carefully monitored during anabolic steroid therapy as anabolic steroids may increase sensitivity to oral anticoagulants which may require a concomitant reduction in anticoagulant dosage to achieve a desirable prothrombin time (PT). Anticoagulant patients should be monitored regularly during anabolic steroid therapy, particularly during initiation and termination of therapy. Warfarin patients should have INR and PT monitored throughout androgen therapy and warfarin dosages titrated to achieve the desired INR and PT. Such patients should be monitored for occult bleeding.
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The foods that you eat may also affect the way this medicine affects your body. Eat a normal, balanced diet while you are taking this medicine. Do not go on a reducing diet, make other changes in your eating habits, start taking vitamins, or begin using other nutrition supplements unless you have first checked with your health care professional. Also, check with your doctor if you are unable to eat for several days or if you have continuing stomach upset, diarrhea, or fever. These precautions are important because the effects of the anticoagulant depend on the amount of vitamin K in your body. Therefore, it is best to have the same amount of vitamin K in your body every day. Some multiple vitamins and some nutrition supplements contain vitamin K. Vitamin K is also present in green, leafy vegetables (such as broccoli, cabbage, collard greens, kale, lettuce, and spinach) and some vegetable oils. It is especially important that you do not make large changes in the amounts of these foods that you eat every day while you are taking an anticoagulant.