Oxymetholone class c



Oxymetholone




(ox i meth’ oh lone)
Anadrol-50
PREGNANCY CATEGORY X
CONTROLLED SUBSTANCE C-III

Drug Classes
Anabolic steroid
Hormone


Therapeutic Actions
Testosterone analogue with androgenic and anabolic activity; promotes body tissue-building processes and reverses catabolic or tissue-depleting processes; increases Hgb and red cell mass.

Indications



  • Anemias caused by deficient red cell production

  • Acquired or congenital aplastic anemia

  • Myelofibrosis and hypoplastic anemias due to myelotoxic drugs

  • Unlabeled use: HIV-associated wasting



Contraindications and Cautions


  • Contraindicated with known sensitivity to oxymetholone or anabolic steroids, prostate or breast cancer, BPH, pituitary insufficiency, MI, nephrosis, liver disease, hypercalcemia, pregnancy, lactation.

  • Use cautiously with diabetes; seizure disorders; migraines; hepatic, cardiac, or renal disease; HF.


Available Forms
Tablets—50 mg

Dosages
Adults and pediatric patients
1–5 mg/kg/day PO. Usual effective dose is 1–2 mg/kg/day. Give for a minimum trial of 3–6 mo. Following remission, patients may be maintained without the drug or on a lower daily dose. Continuous therapy is usually needed in cases of congenital aplastic anemia.
Pediatric patients
Use with extreme caution due to risk of serious disruption of growth and development; weigh benefits and risks.

Pharmacokinetics








Route
Onset

Oral
Rapid

The act contains several references to "derivatives" of compounds but the extent of this term is not fully clarified. Where unspecified it is thought to indicate derivatives which can be made from the specified compound in a single synthetic step, although such a definition would indicate that alkyllysergamide analogues would be uncontrolled. Where the derivatives are specified to be "structural derivatives" there is precedent that the statute applies whenever the structure could be converted to the specified derivatives in any number of synthetic steps. [29]

Oxymethalone is a 17 alpha-alkylated anabolic-androgenic steroid and a synthetic derivative of testosterone, whose anabolic effects are used to treat muscle wasting in HIV patients. The effects of testosterone in humans and other vertebrates occur by way of two main mechanisms: by activation of the androgen receptor (directly or as DHT), and by conversion to estradiol and activation of certain estrogen receptors. Free testosterone (T) is transported into the cytoplasm of target tissue cells, where it can bind to the androgen receptor, or can be reduced to 5α-dihydrotestosterone (DHT) by the cytoplasmic enzyme 5α-reductase. DHT binds to the same androgen receptor even more strongly than T, so that its androgenic potency is about times that of T. The T-receptor or DHT-receptor complex undergoes a structural change that allows it to move into the cell nucleus and bind directly to specific nucleotide sequences of the chromosomal DNA. The areas of binding are called hormone response elements (HREs), and influence transcriptional activity of certain genes, producing the androgen effects.

Some individuals are required to take Anadrol for the rest of their lives.
  Anadrole Before & After Pictures Gained 25 LB lean muscle ★ ★ ★ ★ ★ Gaining 13lbs in 4 weeks and staying lean while still getting stronger was something I’ve not done before! Cole W. VIEW REVIEW Gained 9 LB muscle mass ★ ★ ★ ★ ★ I used to hammer curl 25 pounds I now can do it with 40’s. My before squat was 125 I now can hit 145. Allan Y. VIEW REVIEW Increased bench press by 20 LB ★ ★ ★ ★ ☆ My max bench was 205 before the cycle. After it moved up to 225. My body has shaped up so much more than before. Brandon C. VIEW REVIEW Gained 18 lb of muscle ★ ★ ★ ★ ★ I’ve gained over 18lbs of pure muscle, my biceps have gone from 15 inches to over 18 inches. Tony E. VIEW REVIEW
  Do I Need a Prescription? Anadrol UK laws require a prescription for legal use , and under a certified doctor’s supervision. Anadrol/oxymetholone, is an abused steroid.

As a powerful DHT based anabolic steroid Anadrol can rapidly increase size; it is not uncommon for increases in weight to reach 20-30lbs in mere weeks of use. Further, if that wasnt enough those who supplement with this steroid can expect to see their strength shoot through the roof; strength and size with full and well-rounded muscles, for many performance enhancers this is the end all be all. Of course before you plan any of your Anadrol cycles, although those are some amazing benefits that can be obtained youre going to need to know how to go about it. Contrary to popular culture belief you cannot simply supplement with anabolic steroids; you do not randomly pour a bottle of pills down your throat or arbitrarily jam a needle in your butt; there is planning, doses, length and what to stack.

The long-term use of Anadrol may cause liver blood-filled cysts and tumours. Should you experience any of the following symptoms, it is advisable to immediately stop the administration of the compound and ask for your physician’s advice:
• Nausea
• Upper stomach pain
• Facial and midsection rapid weight gain
• Dark urine and clay-coloured stools
• Jaundice
• Painful or difficult urination
• Sexual disorders (impotence, ongoing erections, decreased libido etc.)
• Painful breasts, hands, or feet swellings
• Difficulty breathing

Oxymetholone class c

oxymetholone class c

Some individuals are required to take Anadrol for the rest of their lives.
  Anadrole Before & After Pictures Gained 25 LB lean muscle ★ ★ ★ ★ ★ Gaining 13lbs in 4 weeks and staying lean while still getting stronger was something I’ve not done before! Cole W. VIEW REVIEW Gained 9 LB muscle mass ★ ★ ★ ★ ★ I used to hammer curl 25 pounds I now can do it with 40’s. My before squat was 125 I now can hit 145. Allan Y. VIEW REVIEW Increased bench press by 20 LB ★ ★ ★ ★ ☆ My max bench was 205 before the cycle. After it moved up to 225. My body has shaped up so much more than before. Brandon C. VIEW REVIEW Gained 18 lb of muscle ★ ★ ★ ★ ★ I’ve gained over 18lbs of pure muscle, my biceps have gone from 15 inches to over 18 inches. Tony E. VIEW REVIEW
  Do I Need a Prescription? Anadrol UK laws require a prescription for legal use , and under a certified doctor’s supervision. Anadrol/oxymetholone, is an abused steroid.

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