The most common daily dose of Anapolon is 100mg, but even at that dosage side-effects like water-retention, elevated blood pressure, acne, hair loss, blood clotting changes, gynocomastia, liver toxicity and mood swings are very often reported. Using aromatase inhibitors to control estrogen aromatization will be ineffective as this drug does not directly convert into estrogen. It was suggested that oxymetholone can activate the estrogen receptor, similar to, but more profoundly than the estrogenic androgen methandriol. Supplements like Milk Thistle can be taken to help keep liver enzyme levels between safe ranges.
Information regarding how the pain is real but not necessarily caused by disease can help to understand the problem. Learning breast self-examination helps to orient the woman to normal and expected texture and structure of the breast and nipple. Yearly breast exams may be suggested. Counseling can also be to describe changes that vary during the monthly cycle. Women on hormone replacement therapy may benefit from a dose adjustment. Another non-pharmacological measure to help relieve symptoms of pain may be to use good bra support. Breasts change during adolescence and menopause and refitting may be beneficial. Applying heat and/or ice can bring relief. Dietary changes may also help with the pain. Methylxanthines can be eliminated from the diet to see if a sensitivity is present. Some clinicians recommending a reduction in salt , though no evidence supports this practice.